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West Palm Beach Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a relationship. Inflammation is the body’s response to damaging stimuli (injury, pathogens, metabolic stress – a disc herniation compressing a nerve!) as it tries to restore itself to normal before the harm was achieved. Chiropractic Care is never shocked at what the body can do! Chiropractic Care sees its West Palm Beach chiropractic care as the body’s partner in healing especially when spine pain is an issue. Chiropractic care uses many tools like spinal manipulation, exercise, and nutrition to help the body. Melatonin is one nutritional tool that is showing value by interrupting the inflammatory process related disc herniation that results in back pain, neck pain and other spine related pain.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are linked to intervertebral disc degeneration. (1) IL-1 β actually promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body regulates itself down to its cellular level via autophagy, the natural process via which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a recent study, melatonin enhanced autophagy and decreased the degradation of the disc’s extracellular matrix (technically marked by a decrease in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The end conclusion was that melatonin inhibits intervertebral disc degeneration by stimulating autophagy. (3) Wow. Chiropractic Care is encouraged by this research to see just how well melatonin can perform for West Palm Beach back pain related to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is quite a common malady seen at Chiropractic Care that positive news of melatonin’s benefits are quite exciting. A new study explained how melatonin could modify the extracellular matrix of the disc remodeling process started by IL-1 β. Further, melatonin decreased the inflammatory cell collection and reduced the release of associated inflammatory markers IL-1β, IL-6, and TNF-α. With this new discovery that melatonin disrupted the IL-1B feedback loop, researchers suggested that melatonin may provide the healing process of intervertebral discs after damage was already present. (1) Chiropractic Care will keep following the new research regarding the role inflammation plays in West Palm Beach disc degeneration and melatonin’s role in combatting it.

INFLAMMATION AND MELATONIN

The importance of melatonin in assisting to slow or stop painful conditions due to inflammation is rising. The description of melatonin as a multitasking molecule affecting mood, immunity, and energy among other things is quite appropriate. It’s also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin influences the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) activities. (1) Melatonin’s specific influence on inflammation and disc degeneration is most attention-getting to Chiropractic Care and our West Palm Beach back pain patients.

CONTACT Chiropractic Care

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she describes how The Cox® Technic System of Spinal Pain Management manages disc degeneration for relief of chronic low back pain in her patient.

Schedule your West Palm Beach chiropractic appointment with Chiropractic Care soon. We can discuss how inflammation affects your back pain and how melatonin may address the related disc degeneration.

 
Chiropractic Care shares new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."